Leader : Michael Hecker
Workpackage leader : Ernst-Moritz-Arndt Universität Greifswald, Pr. Michael Hecker
WP2.1 will generate experimental data about the system components interacting with transcription factors using B. subtilis as a model organism including:
In vivo mapping of TF DNA binding sites under the selected conditions using the ChIP-on-chip technology;
Quantification and post-translational modification of TF in cells under various conditions;
Protein-protein interactions and in vivo protein complexes involving TF.