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Centre national de la recherche scientifique (CNRS)

Location : Montpellier / F
Leader : Franck Molina
Website :

- Description of the institution:

The French National Center for Scientific Research ( CNRS ) is a publicly-funded research organization that defines its mission as producing knowledge and making it available to society. CNRS has 26,000 employees (among which 11,600 researchers and 14,400 engineers and technical and administrative staff). Its amounts to 2.214 billion euros for the year 2004. The 1,260 CNRS service and research units are spread throughout the country and cover all fields of research.

- Description of the different units involved in the project/Competences of the team in the project:

CNRS scientific departments and institutes encompass virtually all fields of knowledge : Nuclear and Particle Physics ( PNC ), Physical Sciences and Mathematics ( SPM ), Communication and Information Science and Technology ( STIC ), Engineering Sciences ( SPI ), Chemical Sciences ( SC ), Earth Sciences and Astronomy ( SDU ), Life Sciences ( SDV ), Humanities and Social Sciences ( SHS ).

The CNRS is involved in BaSysBio project through its research team “biocomputing for systems biology” of the laboratory CNRS UMR 5160 called “Center of Pharmacology and Biotechnology for Health” in Montpellier, France. This team, leaded by Dr Franck Molina, is specialized in three main areas i) complex systems modelling, ii) molecular modelling iii) high throughputs biological data management and analysis.


-The biocomputing research team:

Information system, formal languages for functional description, molecular and systems (multi-scale) modelling, biostatistic (8 CPU cluster)

-The overall laboratory:

Proteomics technologies (2D, Clinprot, Mass spec, SELDI)

Protein interaction analyses : SPR, Multiplex, ELISA

Peptide synthesis, peptides arrays,

Monoclonal antibody engineering

Role in the project: The biocomputing group is involved in WP 3.1 with the development of new methods for multi-scale biological knowledge modelling and heterogeneous data integration; in WP3.2 CNRS will carry out multi-scale modelling; in WP 4.1 they will do innovative biological data quality assessment.

- Key persons involved in BaSysBio:

Dr. Franck Molina

Dr Molina has been crossing disciplines from physic, computing to biology. He combined experimental biology with biocomputing approaches in order to better understand complex autoimmune disorders during his PhD. Then he joined Tom Blundell group in Cambridge for biophysic and biocomputing research on MAP Kinases structures and function. After being recruited at CNRS, he initiated a new project on emerging systems biology and created a new biocomputing for systems biology research group in 2000 in Montpellier. Their original view on biological processes (functions) modelling was distinguished by the bronze medal from CNRS in 2005. Besides academic involvements, Dr. Molina has experienced close relationships with industrial research since more than 15 years. These interactions led to original works patented under current exploitations. He will be the director of the newly created (January 2007) interdisciplinary lab (math, computing, experimental biology) for complex systems modelling and engineering for the diagnostic (CNRS).

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